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Medicine Basics ยท 8 min read

๐Ÿ’Š Painkillers Explained: Paracetamol, Ibuprofen, Aspirin & the Strong Ones

Published August 2026 ยท Reviewed August 2026
PH
PureHealthness Editorial Team ยท Health writers & reviewers
๐Ÿ“ Last reviewed: August 2026
โœ” Transparent sourcing ยท Some articles are AI-drafted, then reviewed & fact-checked by our team
Painkillers Explained: Paracetamol, Ibuprofen, Aspirin & the Strong Ones โ€” real photo

Paracetamol (acetaminophen): reduces pain and fever but barely touches inflammation. Very safe at the right dose โ€” but the maximum adult dose is 4g/day (8ร—500mg tablets), and overdose damages the liver seriously. It is the first choice for fever and everyday pain, safe in pregnancy (short-term) and children (by weight).

Ibuprofen (and other NSAIDs โ€” naproxen, diclofenac): fights pain AND inflammation โ€” better for sprains, muscle aches, toothache and period pain. Take with food; avoid if you have stomach ulcers, kidney disease, or are pregnant (especially after week 20). Max ~1.2g/day OTC (3ร—400mg).

Aspirin: an older NSAID also used in tiny doses (75-100mg) as a blood thinner for heart attack/stroke prevention โ€” but only when a doctor prescribes it; do not start it yourself. Never give aspirin to children or teenagers with fever (Reye's syndrome risk).

Combination warnings: many cold medicines already contain paracetamol โ€” check before adding more. Never take two paracetamol-containing products together.

The strong ones (opioids โ€” codeine, tramadol, morphine): prescription-only, for severe short-term pain (surgery, injury). They work by dulling the brain's pain signal โ€” which is also why they can stop breathing in overdose and are addictive. Never share them; store locked; return leftovers to the pharmacy.

When pain needs a doctor: severe or worsening pain, pain with fever, chest pain, abdominal pain that's sharp, or pain lasting more than a few days without a clear cause. Pain is a signal โ€” don't just mute it forever.

Medicine literacy: understanding how drugs work makes you a safer patient โ€” always check doses, interactions and expiry dates, and never share prescription medicines.

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